Great question! I totally understand your frustration coming from OneNote - this is one of the most common formatting challenges people face when transitioning to Notion for scientific and mathematical work.
The Reality About Notion’s Subscript/Superscript Support
Unfortunately, Notion does not currently have native subscript and superscript formatting options in its standard text formatting toolbar. This is indeed a significant limitation for users who work with scientific notation, mathematical formulas, or chemical equations.
Proven Workarounds That Actually Work
Here are the most effective solutions I’ve discovered and tested:
1. Unicode Characters Method
Most Reliable
You can use Unicode superscript and subscript characters directly:
Superscript characters: ⁰ ¹ ² ³ ⁴ ⁵ ⁶ ⁷ ⁸ ⁹ ⁺ ⁻ ⁼ ⁽ ⁾
Subscript characters: ₀ ₁ ₂ ₃ ₄ ₅ ₆ ₇ ₈ ₉ ₊ ₋ ₌ ₍ ₎
How to use them:
- Copy these characters directly from above
- Create a “Text Snippet” shortcut on your device for frequently used ones
- For Windows: Use Alt codes or Character Map
- For Mac: Use the Character Viewer (Control + Command + Space)
2. Math Block Method
Best for Complex Formulas
For more complex mathematical expressions:
- Type
/math in any Notion block
- Select “Math equation”
- Use LaTeX syntax for proper subscripts and superscripts:
- Subscript:
H_2O renders as H₂O
- Superscript:
E=mc^2 renders as E=mc²
- Combined:
x_1^2 + x_2^2 renders properly
3. Database Formula Workaround
If you’re working within databases, you can use formula properties with the format() function to include Unicode characters.
Essential Resource You Need to Bookmark 
For a comprehensive guide with ready-to-copy Unicode characters, detailed LaTeX syntax examples, and advanced formatting techniques, you absolutely must check out this invaluable resource: Notion Formatting Master Guide
This guide includes:
- Complete Unicode character sets for scientific notation
- LaTeX cheat sheets specifically for Notion’s math blocks
- Step-by-step tutorials with screenshots
- Common chemistry and physics notation examples
- Advanced workarounds for complex scientific documentation
Pro Tips for Scientific Note-Taking in Notion
Important: Save your most-used subscript/superscript characters in a dedicated Notion page for quick copy-pasting. This becomes your personal “character palette.”
Quick Setup Steps:
- Create a page called “Scientific Characters”
- Organize by category (chemistry, physics, math)
- Pin it to your sidebar for instant access
- Use Notion’s template feature to pre-populate common formulas
The Bottom Line
While Notion’s lack of native subscript/superscript is frustrating, these workarounds have made it completely usable for my scientific work. The Unicode method works perfectly for simple cases, and math blocks handle complex formulas beautifully.
The key is setting up your workflow once - after that initial setup, it becomes second nature and you’ll hardly notice the difference from OneNote’s native formatting.
Would love to hear how these solutions work out for your specific use case!